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Oncology

Exelixis licenses oncology compound from Insilico

by Rick Mullin
September 16, 2023 | A version of this story appeared in Volume 101, Issue 31
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Insilico Medicine has licensed to Exelixis the rights to develop and commercialize a molecular inhibitor of ubiquitin specific peptidase 1 (USP1) for the treatment of BRCA-mutated tumors. Under the agreement, Exelixis gains rights to ISM3091 and other USP1-targeting compounds for an up-front payment of $80 million. Insilico says ISM3091 is the third clinical-stage program to emerge from its generative artificial intelligence platform for small-molecule drug discovery.

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