Already have an ACS ID? Log in
Renew your membership, and continue to enjoy these benefits.
Already an ACS Member? Log in here
Choose the membership that is right for you. Discount will be applied automatically at checkout.
Enjoy these benefits no matter which membership you pick.
After synthesizing this indenothiazepinone derivative, Mohamed A. Seleem noticed the branching, tree-like design it made on the walls of this vial. Seleem is a PhD student in the lab of Martin Conda-Sheridan at the University of Nebraska Medical Center studying the antimicrobial activity of this group of compounds against microorganisms like the ones that cause malaria and chlamydia. The structure of the protein that these researchers think they are targeting, ClpX, still has not been solved, so they are modifying the indenothiazepinone molecules and testing their activity against ClpX to see if they can tease out how the protein works and how it’s structured.
Submitted by Mohamed A. Seleem
Do science. Take pictures. Win money. Enter our photo contest here.
Related C&EN Content:
This article has been sent to the following recipient: