ADVERTISEMENT
4 /5 FREE ARTICLES LEFT THIS MONTH Remaining
Chemistry matters. Join us to get the news you need.

If you have an ACS member number, please enter it here so we can link this account to your membership. (optional)

ACS values your privacy. By submitting your information, you are gaining access to C&EN and subscribing to our weekly newsletter. We use the information you provide to make your reading experience better, and we will never sell your data to third party members.

ENJOY UNLIMITED ACCES TO C&EN

Forensic Science

Raman spectra of bloodstains could reveal age range of suspects or victims

Study with blood donors pinpoints age-related intensity differences of particular peaks

by Celia Arnaud
July 1, 2018 | APPEARED IN VOLUME 96, ISSUE 27

 

09627-scicon9-graph.jpg
Credit: Adapted from ACS Cent. Sci.
Two key regions in bloodstain Raman spectra (yellow highlight) differentiate blood donor age ranges.

Bloodstains at a crime scene can provide information about suspects or victims that can guide an investigation. Igor K. Lednev’s group at the University at Albany previously showed that Raman spectra of bloodstains can differentiate races and determine the sex of the individual—without DNA analysis. Now, Lednev and Kyle C. Doty show that Raman can also distinguish among blood from people in different age groups (ACS Cent. Sci. 2018, DOI: 10.1021/acscentsci.8b00198). Lednev and Doty collected spectra of bloodstains from three age groups—infants (younger than one year), adolescents (11–13 years old), and adults (43–68 years old). Hemoglobin dominates Raman spectra of blood when practitioners use an excitation wavelength of 785 nm. The intensity of peaks, particularly those at 375 cm−1 and in the 1,210–1,270 cm−1 region, differentiated the age groups, likely on the basis of small differences in protein secondary structure associated with age. Lednev plans to fill in gaps in the age model by analyzing bloodstains from additional age groups, with the goal of eventually building a model that will be able to determine chronological age rather than just an age group.

X

Article:

This article has been sent to the following recipient:

Leave A Comment

*Required to comment