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Business
Exelixis, Bms in R&D Pact
December 12, 2005
| A version of this story appeared in
Volume 83, Issue 50
Exelixis and Bristol-Myers Squibb are collaborating on therapies targeting the Liver X Receptor (LXR), a nuclear hormone receptor implicated in cardiovascular and metabolic disorders. Exelixis, a nuclear receptor specialist, has identified a series of LXR agonist drug candidates. Under the deal, BMS will undertake preclinical and clinical development as well as the manufacture and sale of any new drug. It will pay Exelixis $17.5 million up front, $10 million annually for two years, and milestone payments that could total $140 million.
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