ADVERTISEMENT
2 /3 FREE ARTICLES LEFT THIS MONTH Remaining
Chemistry matters. Join us to get the news you need.

If you have an ACS member number, please enter it here so we can link this account to your membership. (optional)

ACS values your privacy. By submitting your information, you are gaining access to C&EN and subscribing to our weekly newsletter. We use the information you provide to make your reading experience better, and we will never sell your data to third party members.

ENJOY UNLIMITED ACCES TO C&EN

Analytical Chemistry

SPR Imaging With White Light

June 16, 2008 | APPEARED IN VOLUME 86, ISSUE 24

[+]Enlarge
Credit: Adapted from Phys. Rev. Lett.
The left- and right-handed views of quartz (SiO2) crystals.
Credit: Adapted from Phys. Rev. Lett.
The left- and right-handed views of quartz (SiO2) crystals.

A new surface plasmon resonance (SPR) sensor that is optimized for visible and near-infrared wavelengths could make SPR imaging cheaper and easier to use, according to a study led by chemistry professor Ralph G. Nuzzo and materials science professor John A. Rogers of the University of Illinois, Urbana-Champaign (Angew. Chem. Int. Ed., DOI: 10.1002/anie.200800501). In SPR, polarized light strikes a layer of metal at the interface between media with different refractive indexes, exciting electromagnetic waves called surface plasmons that are sensitive to changes at the interface. The researchers devised an SPR crystal made of an array of gold-coated nanowells. The new device, which is more sensitive at visible and near-IR wavelengths than previous SPR sensors, depends on the diameter, depth, and spacing of the wells and on the thickness of the gold layer. The researchers tested it by using white-light illumination to image 1-octadecanethiol monolayers on the sensor surface. The improved performance in the visible and near-IR spectral regions suggests that such SPR optics could be used with standard laboratory optical microscopes and low-cost charge-coupled device cameras.

X

Article:

This article has been sent to the following recipient:

Leave A Comment

*Required to comment