Volume 87 Issue 11 | p. 48 | Concentrates
Issue Date: March 16, 2009

A Crayon Box For The Biotech Set

DNA-like labels light up biological systems in a rainbow of colors
Department: Science & Technology

By replacing the bases in DNA with different fluorophores, chemists at Stanford University have created a palette of 23 dyes that can be excited at one wavelength (J. Am. Chem. Soc., DOI: 10.1021/ja805502k). The new dyes could find broad use as biological labels, according to the researchers, particularly in systems where classical fluorophores fail, such as in moving organisms. . . .

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