Big Drug Companies Invest In Aileron | June 15, 2009 Issue - Vol. 87 Issue 24 | Chemical & Engineering News
Volume 87 Issue 24 | pp. 15-16 | Concentrates
Issue Date: June 15, 2009

Big Drug Companies Invest In Aileron

Department: Business
Keywords: Aileronrx, stapled peptide

Aileron Therapeutics, a tiny Cambridge, Mass.-based biotech firm focused on developing stapled peptides, has attracted an unusual group of investors in its latest round of financing. In addition to several traditional venture capital firms, the corporate venture funds of GlaxoSmithKline, Novartis, Eli Lilly & Co., and Roche all participated in the $40 million financing round. A stapled peptide is locked into an α-helical shape via cross-links between nonnatural amino acid side chains. Aileron believes their shape and ability to enter cells will allow stapled peptides to access previously unreachable drug targets. This latest influx of cash will allow the company to bring the first stapled peptide drugs into clinical trials next year.

Chemical & Engineering News
ISSN 0009-2347
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