Volume 87 Issue 25 | p. 34 | Concentrates
Issue Date: June 22, 2009

Functional Amyloids

Contrary to their reputation for causing disease, some amyloids have biological functions, including storing and releasing hormones
Department: Science & Technology
Keywords: amyloid, endocrine, Alzheimer's

Amyloids are cross β-sheet-rich peptide or protein aggregates normally thought of as bad actors that cause diseases such as Alzheimer's. But in the past few years, a number of amyloids with normal biological functions have been identified. Roland Riek of the Swiss Federal Institute of Technology, Zurich, and coworkers have added to the tally with the discovery of yet another functional amyloid (Science, DOI: 10.1126/science.1173155). They report that hormones produced by . . .

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