Pfizer Inks Gaucher’s Deal With Protalix | December 7, 2009 Issue - Vol. 87 Issue 49 | Chemical & Engineering News
Volume 87 Issue 49 | p. 23 | Concentrates
Issue Date: December 7, 2009

Pfizer Inks Gaucher’s Deal With Protalix

Department: Business
Keywords: biotechnology, drug development

Pfizer and Israel’s Protalix Biotherapeutics will develop and commercialize taliglu­cer­ase alfa, a form of the enzyme glucocerebrosidase that Protalix produces in genetically engineered carrot cells. The enzyme is deficient in people with Gaucher’s disease, a rare inherited condition related to the breakdown of fat molecules in the body. In return for $60 million up front and up to $55 million in potential milestone payments, Pfizer will get worldwide commercial rights, except in Israel, to the enzyme-replacement therapy. Protalix has completed Phase III trials of the therapy, which has orphan-drug and fast-track status with FDA.

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