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Mersana Therapeutics and Teva Pharmaceuticals have joined forces to develop XMT-1107, Mersana's novel fumagillin analog, which is expected to start Phase I trials in oncology this quarter. Teva will pay the development costs for XMT-1107, and Cambridge, Mass.-based Mersana could get up to $334 million in milestones if the drug candidate works across a range of indications. XMT-1107 prevents blood vessel growth and is linked to Mersana's Fleximer, a biodegradable polymer that improves the drug's safety and pharmacokinetic profile.
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