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Business
Novartis, Array In MEK Inhibitor Pact
by Lisa M. Jarvis
April 26, 2010
| A version of this story appeared in
Volume 88, Issue 17
Novartis has agreed to pay Boulder, Colo.-based Array BioPharma up to $477 million for access to ARRY-162, a MEK inhibitor in Phase I trials as a treatment for solid tumors. Array snags a $45 million up-front payment in the deal, which includes backup MEK inhibitors. The U.S. company will also share in the development costs of ARRY-162 in exchange for a bigger slice of sales if the drug is commercialized. MEK is one of several protein kinases in a cell signaling pathway associated with cancer cell proliferation and survival.
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