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Business

Sanofi And Regulus Sign RNA Pact

by Ann M. Thayer
June 28, 2010 | A version of this story appeared in Volume 88, Issue 26
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Regulus Therapeutics will work with Sanofi-Aventis to develop drugs based on microRNAs, a class of small noncoding RNAs that regulate gene expression. Sanofi will pay $25 million up front and make a $10 million investment in the company in the future. All told, Regulus could receive up to $750 million in fees, R&D funding, and potential milestone payments. The partners will work on four initial micro­RNA targets, and Sanofi has the option to develop others. Isis Pharmaceuticals and Alnylam Pharmaceuticals are joint owners of Regulus.

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