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Pharmaceuticals

Two Pacts Target Modified Antibodies

by Michael McCoy
October 18, 2010 | A version of this story appeared in Volume 88, Issue 42
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Novartis and ImmunoGen will collaborate on drugs based on ImmunoGen’s Targeted Antibody Payload technology. Novartis will pay $45 million for rights to use the technology, which attaches antibodies to potent cancer-killing agents, on several targets. ImmunoGen can also get milestone payments plus compensation for research and manufacturing done for Novartis. Separately, Merck Serono and Ablynx have formed a second agreement to discover therapeutic uses for Nanobodies, antibody-derived proteins from Ablynx said to combine the advantages of conventional antibodies with key small-molecule properties. Ablynx will get a $14 million up-front payment.

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