BMS, Ambrx Partner On Biotherapies | Chemical & Engineering News
Volume 89 Issue 40 | p. 21 | Concentrates
Issue Date: October 3, 2011

BMS, Ambrx Partner On Biotherapies

Department: Business
Keywords: biologics, proteins, hormones

Bristol-Myers Squibb is acquiring worldwide rights to research, develop, and commercialize biologics based on Ambrx’ Fibroblast Growth Factor 21 (FGF-21) protein, a potential treatment for type 2 diabetes, and the hormone relaxin for potential use in treating heart failure. BMS will pay Ambrx $24 million up front and may make milestone and royalty payments. FGF-21 is in late-stage preclinical studies. Relaxin is a naturally occurring hormone known for its role in pregnancy and childbirth. It has been shown in preclinical studies to improve cardiac function.

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