Volume 89 Issue 49 | p. 36 | Concentrates
Issue Date: December 5, 2011

Lipid Fusion Modifies Cell Surfaces

Functionalized liposomes interact with cells to reengineer their surfaces to accept targeted reagents or for assembly into tissues
Department: Science & Technology
News Channels: Biological SCENE
Keywords: cell surface engineering, lipid fusion

Chemists have devised a way to engineer cell surfaces by lipid fusion, a simple technique that involves mixing cells with tailored liposomes. In recent years, scientists have developed genetic and antibiotic engineering techniques to modify cell surfaces with bioorthogonal groups that don’t interfere with natural biomolecules. These groups can be used to better understand cell behavior, target reagents to specific cells, and assemble cells into tissues. Muhammad N. Yousaf of York . . .

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