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Evotec, a German contract research organization, has licensed to Janssen Pharmaceuticals a portfolio of small molecules and biologics designed to trigger the regeneration of insulin-producing beta cells. The antidiabetes compounds were identified by scientists at Harvard University and analyzed by researchers at CureBeta, an R&D joint venture established last year by Evotec, Harvard, and Howard Hughes Medical Institute to develop disease-state-modifying therapeutic targets. Janssen, a division of Johnson & Johnson, will pay $8 million up front and could make milestone payments of up to $300 million per product.
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