Issue Date: December 24, 2012
Heparin Building Blocks Go Upscale
Chemists have devised a synthetic process to make gram-scale amounts of heparin-related oligosaccharides, a development with potential to improve the quality and safety of blood thinners and make available other heparin oligosaccharide medicines. Heparin and heparan sulfate are a family of glycosaminoglycans that play a role in regulating blood-vessel growth, blood coagulation, and the spread of cancer tumors. The clinically used drugs are short-chain oligosaccharides currently isolated from slaughtered pigs and cattle, but chemists would . . .
To view the rest of this content, please log in with your ACS ID.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society