A green tea antioxidant or a common food preservative can enhance microalgae production of lipids for biofuels, reported Diana M. Wong of the University of California, Davis (ACS Chem. Biol., DOI: 10.1021/cb300573r). Wong, Annaliese K. Franz, and colleagues used microplate screening of four microalgae strains to identify small molecules that would promote lipid production but not hinder microalgae growth. Small-molecule concentrations ranged from picomolar to micromolar. The researchers then tested a subset of compounds in 500-mL batch cultures. Included among the promising compounds were the green tea antioxidant epigallocatechin gallate, propyl gallate, and the food preservative butylated hydroxyanisole. Propyl gallate and butylated hydroxyanisole each increased Nannochloropsis salina lipid productivity by more than 60% and would cost 4 cents or less to dose a 50,000-L pond, Wong said.