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Pharmaceuticals

AstraZeneca Licenses Vanderbilt Compounds

by Lisa M. Jarvis
January 21, 2013 | A version of this story appeared in Volume 91, Issue 3
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AstraZeneca has teamed with the Vanderbilt Center for Neuroscience Drug Discovery to discover drugs to treat psychosis associated with major brain diseases. Astra­Zeneca has paid VCNDD an undisclosed sum for the rights to small molecules that act on the M4 muscarinic acetylcholine receptor; the firm will also chip in two years of research funding for the development of those and newer M4 compounds. The deal with AstraZeneca is the latest tie-up for VCNDD and a major drug firm. In September, Bristol-Myers Squibb licensed allosteric modulators of the mGluR4 glutamate receptor from VCNDD.

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