Chemical Invisibility Cloaks Thwart Pesky Mosquitoes | Chemical & Engineering News
Volume 91 Issue 37 | p. 28 | Concentrates
Issue Date: September 16, 2013

Chemical Invisibility Cloaks Thwart Pesky Mosquitoes

ACS Meeting News: Compounds found on the skin can confuse the pesky critters and keep them from biting
Department: Science & Technology | Collection: Life Sciences, Critter Chemistry
News Channels: Biological SCENE, Organic SCENE
Keywords: mosquito, heterocycle, DEET, insecticide

The secret to keeping mosquitoes at bay may be buried within our own skin. Researchers led by Ulrich R. Bernier of USDA’s Agricultural Research Service, in Gainesville, Fla., reported that certain compounds secreted through human skin or formed by bacteria on the skin can render people invisible to mosquitoes. The researchers have been working on the project since the 1990s while trying to answer the question: What makes certain people more attractive than others to mosquitoes? Bernier’s team is still searching for a definitive answer to that question, but meanwhile they have discovered that small heterocycles, such as 1-methylpiperazine, can effectively cloak a person from detection by Aedes aegypti mosquitoes. The compounds don’t work like DEET, or N,N-diethyl-m-toluamide, the active ingredient in many bug sprays that repels the biting insects. Rather, the small heterocycles make it so the mosquitoes don’t realize a person is in the vicinity. The compounds could be used to make novel bite-prevention creams and lotions for folks who don’t like the smell or astringency of DEET. Bernier and colleagues have patented the compounds for these uses (U.S. Patent 8,207,157 B2).

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Dr. Ashish Kumar Sarangi (November 19, 2013 1:33 AM)
It is a nice compounds that use for bite-prevention creams and lotions. Is it used against other harmful insect?
Jack Graham (November 21, 2013 9:56 PM)
Can DEET and 1-methylpiperazine be combined, or do they react?
Andy Kelly (March 7, 2014 1:13 AM)
DEET + 1-methylpiperazine + ethyl pyruvate could be extremely effective as a spray/cream: (see "Targeting a Dual Detector of Skin and CO2 to Modify Mosquito Host Seeking". Genevieve M. Tauxe et al. 2013 Cell 155(6):1365)

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