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Pfizer will work with Eli Lilly & Co. to continue development of tanezumab, a monoclonal antibody it developed for osteoarthritis, back pain, and cancer pain. In 2010, FDA put a partial hold on clinical development of tanezumab because of adverse side effects. FDA may allow trials to restart, pending Pfizer’s submission of nonclinical data in the first half of 2014. A payment by Lilly to Pfizer is contingent on a continuation of the collaboration after FDA responds to the data. Lilly also will make payments to Pfizer for achieving clinical, regulatory, and commercial milestones.
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