Volume 91 Issue 44 | p. 9 | News of The Week
Issue Date: November 4, 2013

Taking Aim At Brain Tumors

Nanomedicine: Gold spheres decorated with RNA block cancer gene expression in mice
Department: Science & Technology
News Channels: Biological SCENE, Materials SCENE, Nano SCENE
Keywords: glioblastoma multiforme, spherical nucleic acid, SNA, RNAi, siRNA

Scientists have created a new weapon to test in the fight against the deadly brain cancer glioblastoma multiforme. By packing strands of small interfering ribonucleic acid, or siRNA, onto the surfaces of gold nanoparticles, they made a nanomedicine that entered the brains of mice and then slipped into tumor cells. There, the siRNA neutralized genes that make those cells flourish.

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Chemical & Engineering News
ISSN 0009-2347
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