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Roche And Polyphor Join For Antibiotic

by Rick Mullin
November 11, 2013 | A version of this story appeared in Volume 91, Issue 45

Two Swiss firms, Roche and Polyphor, have signed an agreement to develop Polyphor’s investigational macrocycle antibiotic to treat hospital-acquired bacterial infections caused by Pseudomonas aeruginosa. Polyphor discovers macrocyclic molecules that kill bacteria by modulating protein-protein interactions. Roche will pay Polyphor $38 million and may make future milestone payments. Polyphor will retain the option to copromote an inhaled formulation of the drug, called POL7080, in Europe.

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