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Pfizer, Cellectis In Immunotherapy Pact

by Lisa M. Jarvis
June 23, 2014 | A version of this story appeared in Volume 92, Issue 25

Pfizer will pay the Paris-based biotech Cellectis $80 million and take a roughly $30 million equity stake in the firm for access to its chimeric antigen receptor T-cell (CAR-T) immunotherapy technology. Pfizer gains exclusive rights to use the CAR-T platform to develop oncology therapies for 15 targets it selects and the right to option therapies based on four targets picked by Cellectis. CAR-T therapy typically involves engineering a patient’s own T cells—a type of white blood cell—to attack cancer cells. Cellectis has found a way to use T cells from a single donor in multiple patients.

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