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Biogen Idec will work with Sangamo BioSciences on developing treatments for inherited conditions related to the abnormal structure or underproduction of hemoglobin, such as sickle cell disease and β-thalassemia. Sangamo’s zinc finger nuclease genome-editing technology will allow the partners to precisely target and knock out key regulators of gene expression or insert a corrective gene to replace the defective copy. Biogen Idec will pay Sangamo $20 million up front and support R&D. Sangamo could receive another $300 million in milestone payments.
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