Volume 93 Issue 16 | p. 3 | News of The Week
Issue Date: April 20, 2015 | Web Date: April 16, 2015

Structure Of The Measles Virus Nucleocapsid Reveals How It Wraps Up Its Genome

Structural Biology: Researchers tame the virus’s floppy capsid structure using cryo-electron microscopy
Department: Science & Technology
News Channels: Biological SCENE, Analytical SCENE
Keywords: measles, virus, capsid, cryo electron microscopy

Cryo-electron microscopy has given scientists the first glimpse at how the measles virus wraps up its genome in its protective protein container. The 4.3-Å structure provides a platform for understanding viral replication and transcription and could enable the development of measles antiviral drugs, says Irina Gutsche, at the National Center for Scientific Research (CNRS), in Grenoble, France, who led the team of researchers.

The structure is also the first nearly atomic-resolution reconstruction . . .

To view the rest of this content, please log in with your ACS ID.

Chemical & Engineering News
ISSN 0009-2347
Copyright © American Chemical Society