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Intrexon To Acquire Protein Drug Firm

by Ann M. Thayer
February 23, 2015 | A version of this story appeared in Volume 93, Issue 8

Intrexon will pay $60 million in cash and stock to acquire the biopharmaceutical firm ActoGenix. Based in Ghent, Belgium, ActoGenix engineers food-grade Lactococcus lactis microbes it calls ActoBiotics to secrete therapeutic proteins in the oral and gastrointestinal tract. Now in clinical trials, the company’s AG013 delivers a peptide for preventing and controlling oral mucositis; AG014 secretes an anti-TNFα antibody to treat inflammatory bowel disease. Intrexon applies its synthetic biology capabilities to create cellular and gene therapies and to produce active ingredients.

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