Microbes help make ambergris scent | Chemical & Engineering News
Volume 94 Issue 10 | p. 17 | Concentrates
Issue Date: March 7, 2016

Microbes help make ambergris scent

Department: Business
Keywords: biobased chemicals, flavors and fragrance, biotechnology

Firmenich says it has scaled up a new route to Ambrox, a woody-scented fragrance molecule, with an assist from microbes. Ambrox , known generically as ambroxide, is a component of ambergris, an excretion from the digestive tract of sperm whales. Because ambergris is rare, the fragrance industry has long relied on a semisynthetic process to make it from sclareol, which is isolated from the herb clary sage. Firmenich scientists engineered microbes to make sclareol from sugar.

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