Issue Date: December 5, 2016
Arrowhead sheds programs, staff
In a surprise move, Arrowhead Pharmaceuticals is discontinuing development of multiple RNAi drug candidates that use the same delivery technology. The decision comes just weeks after FDA placed a hold on a clinical trial of ARC-520, a hepatitis B treatment, following the death of several non-human primates in a preclinical toxicology study of the drug. Arrowhead is abandoning three programs—ARC-520, ARC-521, and ARC-AAT—that use the same liver-targeted, intravenously administered delivery vehicle. Arrowhead will refocus its . . .
To view the rest of this content, please log in with your ACS ID.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society