Volume 95 Issue 29 | p. 11 | Concentrates
Issue Date: July 17, 2017

Plausible prebiotic route to iron-sulfur clusters identified

Cluster synthesis driven by UV light uses iron ions and tripeptide starting material
Department: Science & Technology
News Channels: Biological SCENE
Keywords: origins of life, biological chemistry, enzymes, cofactors, Fe-S clusters

Iron-sulfur clusters are important cofactors required for the catalytic sites of various enzymes. Researchers have hypothesized that such clusters may have even been involved in the emergence of biological catalysis on early Earth. Such a role would have required spontaneous formation of these clusters from environmental sources, so identifying a plausible route has been a major goal in the field of prebiotic chemistry. Now, Sheref S. Mansy of the University of Trento . . .

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