Volume 95 Issue 40 | p. 9 | News of The Week
Issue Date: October 9, 2017 | Web Date: October 4, 2017

Fluorescent sensor measures ionic strength in living cells

First in vivo ionic strength sensor could identify variations within a cell
Department: Science & Technology
Keywords: biochemistry, analytical chemistry, ionic strength, FRET, biosensor

A fluorescent biosensor is the first to quantify the ionic strength inside living cells (ACS Chem. Biol. 2017, DOI: 10.1021/acschembio.7b00348). The sensor could enable cell biologists to follow changes in ionic strength over time or at different locations in a cell, changes that are key for controlling protein aggregation.

Ionic strength measures the concentration of unbound ions floating in a cell. It affects many biological processes including protein . . .

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