Photoacoustic molecular probe detects hypoxia | December 4, 2017 Issue - Vol. 95 Issue 48 | Chemical & Engineering News
Volume 95 Issue 48 | p. 10 | Concentrates
Issue Date: December 4, 2017

Photoacoustic molecular probe detects hypoxia

Low oxygen levels trigger a switch from N-oxide to aniline, with an observable spectral signature
Department: Science & Technology
Keywords: Imaging, hypoxia, photoacoustic

Hypoxia—damage to tissue caused by low oxygen levels—can be difficult to detect. Jefferson Chan and coworkers at the University of Illinois, Urbana-Champaign, have developed a small molecule probe they call HyP-1 that improves hypoxia detection by using photoacoustic imaging (Nat. Commun. 2017, DOI: 10.1038/s41467-017-01951-0). In photoacoustic imaging, near-infrared light induces temperature and pressure changes in tissue that result in the . . .

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