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Business
Incyte, Calithera join for arginase inhibitor
by Ann M. Thayer
February 6, 2017
| A version of this story appeared in
Volume 95, Issue 6
Incyte and Calithera Biosciences will work together to develop Calithera’s small-molecule arginase inhibitor CB-1158. Incyte will pay Calithera $45 million up front and make an $8 million equity investment. Calithera could receive up to $750 million in milestone payments. The molecule is being tested alone in early-stage hematology and oncology trials. The companies also expect to explore its use in combination with immuno-oncology agents such as anti-PD-1 therapies.
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