Seattle Genetics acquires Cascadian | February 5, 2018 Issue - Vol. 96 Issue 6 | Chemical & Engineering News
Volume 96 Issue 6 | p. 15 | Concentrates
Issue Date: February 5, 2018

Seattle Genetics acquires Cascadian

Department: Business
Keywords: Oncology, pharmaceuticals, biotech

Antibody-drug-conjugate-focused Seattle Genetics is shelling out roughly $614 million in cash to acquire Cascadian Therapeutics, a Seattle-based biotech focused on oncology. The centerpiece of the deal is tucatinib, a HER2 receptor inhibitor currently in Phase II trials as a treatment for people with HER2+ metastatic breast cancer. While two approved drugs, the antibody Herceptin and the antibody-drug conjugate Kadcyla, also target the HER2 receptor, tucatinib is an orally available small molecule, licensed to Cascadian from Array BioPharma.

Chemical & Engineering News
ISSN 0009-2347
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