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Biological Chemistry
Chemistry In Pictures
Chemistry in Pictures: Van Gogh’s Worrisome Brain Chemistry
by Craig Bettenhausen
November 1, 2022
Credit: Submitted by Kazushige Yokoyama
The flowing line work, the pastel-icized color palette, the off-center emphasis evoking imbalance, the brushed texture, all hallmarks of Vincent Van Gogh’s signature style and all created here by evaporation and protein crystallization. What we have here is not an abstract work by the famous Dutch master, but rather a visible-light microscopy image of image of 20-nm gold colloidal particles coated with amyloid β 12–18 and dispersed on a slice of mica. Geneseo University professor Kazushige Yokoyama prepared this sample as part of his work using nanoparticles to probe the formation of protein aggregates in the brain, a phenomenon suspected to be part of dementia, Alzheimer’s, and other neurodegenerative diseases.
Submitted by Kazushige Yokoyama
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Chemical & Engineering News
ISSN 0009-2347
Copyright © 2024 American Chemical Society
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