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Regeneron has expanded the collaboration it began in 2016 with the CRISPR gene-editing company Intellia Therapeutics. The two firms will codevelop an in vivo therapy for hemophilia A and B that uses CRISPR to insert a blood clotting–factor gene into liver cells. Regeneron will pay Intellia $70 million up front and purchase $30 million of the company’s stock. Regeneron also has the rights to develop up to 15 more in vivo CRISPR therapies with Intellia and up to 10 gene-edited cell therapies.
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