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Most Popular in Biological Chemistry
Less than 18 months after Beam Therapeutics launched with its first round of private funding, the gene-editing start-up has filed paperwork for a $100 million initial public offering on Nasdaq. Beam is developing therapies derived from the CRISPR base editors invented in David Liu’s lab at the Broad Institute of MIT & Harvard. Liu’s editors, published in 2016, can change a single nucleotide of DNA into another nucleotide. Beam is working on 12 drug programs, with an initial focus on blood, liver, and eye diseases, as well as CAR T-cell therapies.
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