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Neuroscience

Nitrome raises $38 million to drug Parkinson’s enzyme

by Ryan Cross
April 24, 2020 | A version of this story appeared in Volume 98, Issue 16
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San Francisco–based Nitrome Biosciences has raised $38 million in series A financing to develop small-molecule drugs for Parkinson’s disease. Nitrome CEO Irene Griswold-Prenner cofounded the company in 2018 to look for enzymes thought to catalyze nitration of alpha-synuclein, a protein that aggregates in the brains of people with Parkinson’s disease. The start-up discovered a family of such enzymes that it dubbed nitrases. The financing was led by Sofinnova Partners and AbbVie Ventures.

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