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Passage Bio, a gene therapy start-up cofounded in 2019 by University of Pennsylvania scientist James Wilson, is cutting about 13% of its workforce as part of a plan to conserve cash. At the end of 2021 the company had 133 employees, 85 of whom were in R&D or technical roles. The firm’s chief R&D officer, Eliseo O. Salinas, will also leave. Passage has three gene therapies in clinical trials for central nervous system disorders, including frontotemporal dementia.
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