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Investment

Xencor earns $120 million from Genentech for IL-15 antibody

by Ryan Cross
February 8, 2019 | A version of this story appeared in Volume 97, Issue 6
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Genentech will pay $120 million up front to partner with the antibody company Xencor on new cancer immunotherapies based on a protein called interleukin-15 (IL-15). Xencor’s lead program in the partnership combines IL-15 and its receptor, IL-15Rα, into a single protein designed to activate immune cells that can attack cancer. Xencor could receive up to $160 million more for developing the lead candidate and up to $180 million for each subsequent IL-15 drug.

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