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Novartis has signed a deal to acquire Gyroscope Therapeutics, a UK-based ocular gene therapy company, for $800 million plus potential milestone payments of up to $700 million. Gyroscope is developing GT005, a one-time gene therapy for geographic atrophy, an advanced form of dry age-related macular degeneration. GT005 works by increasing production of a protein that regulates inflammation. Novartis markets Roche’s Luxturna, a gene therapy for retinal dystrophy, outside the US.
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