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Start-ups

Brain organoid start-up System1 Biosciences raises $25 million for neuropsychiatric drug discovery

by Ryan Cross
September 22, 2018 | A version of this story appeared in Volume 96, Issue 38
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System1 Biosciences has raised $25 million in series A financing for its autism, epilepsy, and schizophrenia drug discovery programs. The San Francisco-based start-up will tackle the tough-to-treat conditions by testing drugs on cerebral organoids, which are miniature brainlike organs grown in a lab. System1 is growing its organoids with stem cells from patients with a brain disease. The firm hopes that organoids will provide a more realistic preclinical model than the cells and animals often used in neuropsychiatric drug discovery.

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