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Start-ups

Cullgen raises $16 million series A for targeted protein degraders

by Ryan Cross
April 20, 2019 | A version of this story appeared in Volume 97, Issue 16

 

San Diego–based Cullgen is the latest start-up launching with plans to develop targeted protein degraders—small molecules that bind a disease-causing protein at one end and tag it for destruction by the cell’s protein-recycling machinery at the other end. The venture capital firms Sequoia Capital China and HighLight Capital together invested $16 million in Cullgen’s series A financing. Cullgen’s initial focus is on cancer, as well as autoimmune and inflammatory diseases.

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