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Start-ups

Sibylla nets $23 million series A to target folded proteins

by Shi En Kim
October 8, 2022 | A version of this story appeared in Volume 100, Issue 36
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Sibylla Biotech has closed $23 million in series A financing. The Italian firm uses a protein-folding simulation platform to identify transient folding intermediates in proteins that are undruggable in their static states. The biotech’s drug pipeline consists of small-molecule degraders that disrupt the folding process of disease-linked proteins, thereby suppressing their expression. Sibylla’s lead candidate targets the cyclin D1 protein, which is overexpressed in cancer.

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