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Pharmaceuticals

Celgene takes option on Triphase WDR5 compound

by Lisa Jarvis
February 1, 2019 | A version of this story appeared in Volume 97, Issue 5

 

Celgene will pay $40 million up front for an option to acquire Triphase Accelerator’s small molecule targeting WDR5 protein, a key player in the formation of protein complexes that indirectly modify genes. Leukemia and other blood cancers can arise due to the misregulation of WDR5-associated protein complexes. The deal for the preclinical compound is Celgene’s third cancer pact since Bristol-Myers Squibb announced it would buy the New Jersey­–based company for $74 billion last month.

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