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Pharmaceuticals

Periodic Graphics

Periodic Graphics: 6 unusual side effects of medicines

Chemical educator and Compound Interest blogger Andy Brunning looks at the compounds behind some strange side effects.

by Andy Brunning, special to C&EN
July 2, 2023 | A version of this story appeared in Volume 101, Issue 21
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Infographic detailing six unusual side effects of some medications and how they arise. The six side effects are compulsive behaviors, caused by some medicines that treat Parkinson’s disease symptoms; light sensitivity, caused by medicines including tetracyclines; sleep disorders, which are caused by some sleeping pills; changes to stool or urine color, such as from Pepto-Bismol; tooth staining, which can occur with tetracycline antibiotics; and vanishing fingerprints, a side effect of the chemotherapy drug capecitabine.


To download a pdf of this article, visit cenm.ag/sideeffects.

References used to create this graphic:

Bostwick, J. Michael, Kathleen A. Hecksel, Susanna R. Stevens, James H. Bower, and J. Eric Ahlskog. “Frequency of New-Onset Pathologic Compulsive Gambling or Hypersexuality after Drug Treatment of Idiopathic Parkinson Disease.” Mayo Clin. Proc. (2009). DOI: 10.1016/S0025-6196(11)60538-7.

Hofmann, Georg Amun, and Benedikt Weber. “Drug-Induced Photosensitivity: Culprit Drugs, Potential Mechanisms and Clinical Consequences.” J. Deutschen Dermatologischen Gesellschaft (2021). DOI: 10.1111/ddg.14314.

Hoque, Romy, and Andrew L. Chesson. “Zolpidem-Induced Sleepwalking, Sleep Related Eating Disorder, and Sleep-Driving: Fluorine-18-Flourodeoxyglucose Positron Emission Tomography Analysis, and a Literature Review of Other Unexpected Clinical Effects of Zolpidem.” J. Clin. Sleep Med. (2009). DOI: 10.5664/jcsm.27605.

Lightowlers, Sara, and Rubin Soomal. “Loss of Fingerprints Secondary to Palmoplantar Erythrodysesthesia in a Patient on Capecitabine Chemotherapy.” BMJ (2015). DOI: 10.1136/bmj.h6023.

Sanchez, Andrés R., Roy S. Rogers III, and Phillip J. Sheridan. “Tetracycline and Other Tetracycline-Derivative Staining of the Teeth and Oral Cavity.” Int. J. Dermatol. (2004). DOI: 10.1111/j.1365-4632.2004.02108.x

A collaboration between C&EN and Andy Brunning, author of the popular graphics blog Compound Interest

To see more of Brunning’s work, go to compoundchem.com. To see all of C&EN’s Periodic Graphics, visit cenm.ag/periodicgraphics.

 

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