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Generian Pharmaceuticals and Mitobridge, a subsidiary of Astellas Pharma, have formed a partnership to identify and develop small molecules that modulate undruggable protein targets in diseases with limited treatment options. Astellas will pay Generian up to $180 million and be responsible for clinical development. Separately, Dunad Therapeutics, a company focused on small-molecule protein degraders, has appointed Pearl Huang CEO. Huang has held leadership positions at Roche, GSK, Merck & Co., and, most recently, Cygnal Therapeutics.
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