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Antibiotics

Anixa to start CAR-T trial for ovarian cancer

by Megha Satyanarayana
September 2, 2021 | A version of this story appeared in Volume 99, Issue 32
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The US Food and Drug Administration has accepted Anixa Biosciences’s investigational new drug application, clearing the company to begin clinical trials of its chimeric antigen receptor T-cell (CAR-T) treatment for ovarian cancer. Moffitt Cancer Center developed the therapy, which consists of T cells from a person with ovarian cancer that are engineered to recognize the follicle stimulating hormone receptor. CAR-T has been successful in treating blood cancers but has been difficult to adapt to solid tumors.

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