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Drug Development

GSK and Mersana sign $100 million antibody-drug conjugate pact

by Gina Vitale
August 14, 2022 | A version of this story appeared in Volume 100, Issue 28
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GSK will pay Mersana Therapeutics, an antibody-drug conjugate (ADC) specialist, $100 million for the option to codevelop and commercialize XMT-2056, an ADC that targets the protein HER2. Mersana intends to test the drug in Phase 1 trials against several types of HER2-expressing tumors such as breast, gastric, and non-small-cell lung cancers, the companies say. Mersana is eligible to receive up to $1.36 billion in further payments if GSK exercises its option.

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