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Neurocrine Biosciences will pay Sosei Heptares $100 million to partner on developing small-molecule drugs for schizophrenia, dementia, and other neuropsychiatric disorders. Sosei’s compounds target specific muscarinic receptors and could have fewer side effects than drugs that target multiple receptors. Neurocrine plans a Phase 2 study next year of a selective M4 muscarinic receptor agonist for schizophrenia.
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